I have a Plugable USB3-HUB10C
It is plugged into the intel ports of an Asus Z170-Premium (BIOS 1902) under Windows 10 AU (14393.105)
I have 3 HD’s attached to the hub (spaced to be one per chip via the diagram), 2 are powered by external wall-warts, one is powered by the bus. The rest of the ports are empty. The drivers being used are the default Microsoft drivers (USB3HUB.SYS V10.0.14393.0).